LymphedemaV1, PascalFrancis, Corpus, bibRecord, 000C16

Ultrastructural observations of lymphatic vessels in lymphedema in human extremities. Discussion

Identifieur interne : 000C16 ( PascalFrancis/Corpus ); précédent : 000C15; suivant : 000C17

Ultrastructural observations of lymphatic vessels in lymphedema in human extremities. Discussion

Auteurs : I. Koshima ; S. Kawada ; T. Moriguchi ; Y. Kajiwara ; M. Földi

Source :

Plastic and reconstructive surgery : (1963) [ 0032-1052 ] ; 1996.

RBID : Pascal:96-0130969

Descripteurs français

Pascal (Inist)
- Lymphoedème, Traitement, Anastomose chirurgicale, Lymphaticoveineux, Exploration, Préopératoire, Anatomopathologie, Ultrastructure, Pronostic, Etude cas, Adulte.

English descriptors

KwdEn :
- Adult, Case study, Exploration, Lymphaticovenous, Lymphedema, Pathology, Preoperative, Prognosis, Surgical anastomosis, Treatment, Ultrastructure.

Abstract

Microsurgical lymphaticovenous anastomoses were done on a total of 14 patients. Six upper extremities of six female patients (average age 56.5 years) were operated on with lymphaticovenous anastomoses and were followed up for 17 months or more after surgery (average 25.5 months). Twelve legs of eight patients (average age 44.6 years) also were operated on and followed up for 12 months or more after surgery (average 23.4 months). Among these patients, 33 biopsied lymphatic trunks with lymphedema in 16 extremities of 12 patients were evaluated histologically by light and electron microscopy. Regarding the operative effect in the arms, the decreased circumference of the arms ranged from 2 to 9 cm (average 5.3 cm). The rate of preoperative versus postoperative excess circumference decreased in range from 25 to 94.7 percent (average 65.7 percent). As for the surgical effect in the legs, half the legs showed improvement. These postoperative improvements showed no correlation with the preoperative duration of edema and excess circumference in either the upper or lower extremities. Histologically, in the initial stage of lymphedema, there was destruction of both endothelial cells and smooth muscle cells in the proximal level of the lymphatic trunks. The lumen of some proximal trunks was then occluded by organization with a few small recanalizations, but the distal lymphatics remained patent with minimal destruction of both the endothelial cells and the smooth muscle cells even in the later stage of lymphedema. These results suggest that the occlusions of the lymphatic trunks and degeneration of the smooth muscle cells may start from the proximal ends of the extremities and that the timing of the occlusions and the degeneration of smooth muscle cells may not correspond to the duration of edema. It is also considered that because of the smooth muscle degeneration, the lymph-drainage capacity of the lymphatic trunks may be remarkably weakened in the proximal lymphatics of the extremities. Therefore, it is suggested that the remaining lymphatic drainage function with the smooth muscle cells may correlate with the postoperative improvement of edema. It is also suggested that the preoperative ultrastructural examination of the lymph-drainage capacity may be a suitable method for predicting the surgical effect and operative indication for lymphatic edema in the extremities.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A11	`03`	`1`		`@1 MORIGUCHI (T.)`
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C01	`01`		`ENG`	@0 Microsurgical lymphaticovenous anastomoses were done on a total of 14 patients. Six upper extremities of six female patients (average age 56.5 years) were operated on with lymphaticovenous anastomoses and were followed up for 17 months or more after surgery (average 25.5 months). Twelve legs of eight patients (average age 44.6 years) also were operated on and followed up for 12 months or more after surgery (average 23.4 months). Among these patients, 33 biopsied lymphatic trunks with lymphedema in 16 extremities of 12 patients were evaluated histologically by light and electron microscopy. Regarding the operative effect in the arms, the decreased circumference of the arms ranged from 2 to 9 cm (average 5.3 cm). The rate of preoperative versus postoperative excess circumference decreased in range from 25 to 94.7 percent (average 65.7 percent). As for the surgical effect in the legs, half the legs showed improvement. These postoperative improvements showed no correlation with the preoperative duration of edema and excess circumference in either the upper or lower extremities. Histologically, in the initial stage of lymphedema, there was destruction of both endothelial cells and smooth muscle cells in the proximal level of the lymphatic trunks. The lumen of some proximal trunks was then occluded by organization with a few small recanalizations, but the distal lymphatics remained patent with minimal destruction of both the endothelial cells and the smooth muscle cells even in the later stage of lymphedema. These results suggest that the occlusions of the lymphatic trunks and degeneration of the smooth muscle cells may start from the proximal ends of the extremities and that the timing of the occlusions and the degeneration of smooth muscle cells may not correspond to the duration of edema. It is also considered that because of the smooth muscle degeneration, the lymph-drainage capacity of the lymphatic trunks may be remarkably weakened in the proximal lymphatics of the extremities. Therefore, it is suggested that the remaining lymphatic drainage function with the smooth muscle cells may correlate with the postoperative improvement of edema. It is also suggested that the preoperative ultrastructural examination of the lymph-drainage capacity may be a suitable method for predicting the surgical effect and operative indication for lymphatic edema in the extremities.
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Format Inist (serveur)

NO :	PASCAL 96-0130969 INIST
ET :	Ultrastructural observations of lymphatic vessels in lymphedema in human extremities. Discussion
AU :	KOSHIMA (I.); KAWADA (S.); MORIGUCHI (T.); KAJIWARA (Y.); FÖLDI (M.)
AF :	Kawasaki medical school, dep. plastic reconstructive surgery and radiology/Kurashiki-City, Okayama 701-01/Japon (1 aut., 2 aut., 3 aut., 4 aut.)
DT :	Publication en série; Article; Commentaire; Niveau analytique
SO :	Plastic and reconstructive surgery : (1963); ISSN 0032-1052; Etats-Unis; Da. 1996; Vol. 97; No. 2; Pp. 397-407; Bibl. 17 ref.
LA :	Anglais
EA :	Microsurgical lymphaticovenous anastomoses were done on a total of 14 patients. Six upper extremities of six female patients (average age 56.5 years) were operated on with lymphaticovenous anastomoses and were followed up for 17 months or more after surgery (average 25.5 months). Twelve legs of eight patients (average age 44.6 years) also were operated on and followed up for 12 months or more after surgery (average 23.4 months). Among these patients, 33 biopsied lymphatic trunks with lymphedema in 16 extremities of 12 patients were evaluated histologically by light and electron microscopy. Regarding the operative effect in the arms, the decreased circumference of the arms ranged from 2 to 9 cm (average 5.3 cm). The rate of preoperative versus postoperative excess circumference decreased in range from 25 to 94.7 percent (average 65.7 percent). As for the surgical effect in the legs, half the legs showed improvement. These postoperative improvements showed no correlation with the preoperative duration of edema and excess circumference in either the upper or lower extremities. Histologically, in the initial stage of lymphedema, there was destruction of both endothelial cells and smooth muscle cells in the proximal level of the lymphatic trunks. The lumen of some proximal trunks was then occluded by organization with a few small recanalizations, but the distal lymphatics remained patent with minimal destruction of both the endothelial cells and the smooth muscle cells even in the later stage of lymphedema. These results suggest that the occlusions of the lymphatic trunks and degeneration of the smooth muscle cells may start from the proximal ends of the extremities and that the timing of the occlusions and the degeneration of smooth muscle cells may not correspond to the duration of edema. It is also considered that because of the smooth muscle degeneration, the lymph-drainage capacity of the lymphatic trunks may be remarkably weakened in the proximal lymphatics of the extremities. Therefore, it is suggested that the remaining lymphatic drainage function with the smooth muscle cells may correlate with the postoperative improvement of edema. It is also suggested that the preoperative ultrastructural examination of the lymph-drainage capacity may be a suitable method for predicting the surgical effect and operative indication for lymphatic edema in the extremities.
CC :	002B12B04
FD :	Lymphoedème; Traitement; Anastomose chirurgicale; Lymphaticoveineux; Exploration; Préopératoire; Anatomopathologie; Ultrastructure; Pronostic; Etude cas; Adulte
FG :	Homme; Appareil circulatoire pathologie; Lymphatique pathologie; Chirurgie
ED :	Lymphedema; Treatment; Surgical anastomosis; Lymphaticovenous; Exploration; Preoperative; Pathology; Ultrastructure; Prognosis; Case study; Adult
EG :	Human; Cardiovascular disease; Lymphatic vessel disease; Surgery
GD :	Aufbereiten
SD :	Linfedema; Tratamiento; Anastomosis quirúrgica; Linfaticovenoso; Exploración; Preoperatorio; Anatomía patológica; Ultraestructura; Pronóstico; Estudio caso; Adulto
LO :	INIST-11075.354000052734390160
ID :	96-0130969

Links to Exploration step

Pascal:96-0130969

Le document en format XML

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<front><div type="abstract" xml:lang="en">Microsurgical lymphaticovenous anastomoses were done on a total of 14 patients. Six upper extremities of six female patients (average age 56.5 years) were operated on with lymphaticovenous anastomoses and were followed up for 17 months or more after surgery (average 25.5 months). Twelve legs of eight patients (average age 44.6 years) also were operated on and followed up for 12 months or more after surgery (average 23.4 months). Among these patients, 33 biopsied lymphatic trunks with lymphedema in 16 extremities of 12 patients were evaluated histologically by light and electron microscopy. Regarding the operative effect in the arms, the decreased circumference of the arms ranged from 2 to 9 cm (average 5.3 cm). The rate of preoperative versus postoperative excess circumference decreased in range from 25 to 94.7 percent (average 65.7 percent). As for the surgical effect in the legs, half the legs showed improvement. These postoperative improvements showed no correlation with the preoperative duration of edema and excess circumference in either the upper or lower extremities. Histologically, in the initial stage of lymphedema, there was destruction of both endothelial cells and smooth muscle cells in the proximal level of the lymphatic trunks. The lumen of some proximal trunks was then occluded by organization with a few small recanalizations, but the distal lymphatics remained patent with minimal destruction of both the endothelial cells and the smooth muscle cells even in the later stage of lymphedema. These results suggest that the occlusions of the lymphatic trunks and degeneration of the smooth muscle cells may start from the proximal ends of the extremities and that the timing of the occlusions and the degeneration of smooth muscle cells may not correspond to the duration of edema. It is also considered that because of the smooth muscle degeneration, the lymph-drainage capacity of the lymphatic trunks may be remarkably weakened in the proximal lymphatics of the extremities. Therefore, it is suggested that the remaining lymphatic drainage function with the smooth muscle cells may correlate with the postoperative improvement of edema. It is also suggested that the preoperative ultrastructural examination of the lymph-drainage capacity may be a suitable method for predicting the surgical effect and operative indication for lymphatic edema in the extremities.</div>
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<fC01 i1="01" l="ENG"><s0>Microsurgical lymphaticovenous anastomoses were done on a total of 14 patients. Six upper extremities of six female patients (average age 56.5 years) were operated on with lymphaticovenous anastomoses and were followed up for 17 months or more after surgery (average 25.5 months). Twelve legs of eight patients (average age 44.6 years) also were operated on and followed up for 12 months or more after surgery (average 23.4 months). Among these patients, 33 biopsied lymphatic trunks with lymphedema in 16 extremities of 12 patients were evaluated histologically by light and electron microscopy. Regarding the operative effect in the arms, the decreased circumference of the arms ranged from 2 to 9 cm (average 5.3 cm). The rate of preoperative versus postoperative excess circumference decreased in range from 25 to 94.7 percent (average 65.7 percent). As for the surgical effect in the legs, half the legs showed improvement. These postoperative improvements showed no correlation with the preoperative duration of edema and excess circumference in either the upper or lower extremities. Histologically, in the initial stage of lymphedema, there was destruction of both endothelial cells and smooth muscle cells in the proximal level of the lymphatic trunks. The lumen of some proximal trunks was then occluded by organization with a few small recanalizations, but the distal lymphatics remained patent with minimal destruction of both the endothelial cells and the smooth muscle cells even in the later stage of lymphedema. These results suggest that the occlusions of the lymphatic trunks and degeneration of the smooth muscle cells may start from the proximal ends of the extremities and that the timing of the occlusions and the degeneration of smooth muscle cells may not correspond to the duration of edema. It is also considered that because of the smooth muscle degeneration, the lymph-drainage capacity of the lymphatic trunks may be remarkably weakened in the proximal lymphatics of the extremities. Therefore, it is suggested that the remaining lymphatic drainage function with the smooth muscle cells may correlate with the postoperative improvement of edema. It is also suggested that the preoperative ultrastructural examination of the lymph-drainage capacity may be a suitable method for predicting the surgical effect and operative indication for lymphatic edema in the extremities.</s0>
</fC01>
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</fC07>
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<fC07 i1="01" i2="X" l="SPA"><s0>Hombre</s0>
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<s5>37</s5>
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<s5>38</s5>
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<fC07 i1="03" i2="X" l="ENG"><s0>Lymphatic vessel disease</s0>
<s5>38</s5>
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<fC07 i1="03" i2="X" l="SPA"><s0>Linfático patología</s0>
<s5>38</s5>
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<s5>45</s5>
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<server><NO>PASCAL 96-0130969 INIST</NO>
<ET>Ultrastructural observations of lymphatic vessels in lymphedema in human extremities. Discussion</ET>
<AU>KOSHIMA (I.); KAWADA (S.); MORIGUCHI (T.); KAJIWARA (Y.); FÖLDI (M.)</AU>
<AF>Kawasaki medical school, dep. plastic reconstructive surgery and radiology/Kurashiki-City, Okayama 701-01/Japon (1 aut., 2 aut., 3 aut., 4 aut.)</AF>
<DT>Publication en série; Article; Commentaire; Niveau analytique</DT>
<SO>Plastic and reconstructive surgery : (1963); ISSN 0032-1052; Etats-Unis; Da. 1996; Vol. 97; No. 2; Pp. 397-407; Bibl. 17 ref.</SO>
<LA>Anglais</LA>
<EA>Microsurgical lymphaticovenous anastomoses were done on a total of 14 patients. Six upper extremities of six female patients (average age 56.5 years) were operated on with lymphaticovenous anastomoses and were followed up for 17 months or more after surgery (average 25.5 months). Twelve legs of eight patients (average age 44.6 years) also were operated on and followed up for 12 months or more after surgery (average 23.4 months). Among these patients, 33 biopsied lymphatic trunks with lymphedema in 16 extremities of 12 patients were evaluated histologically by light and electron microscopy. Regarding the operative effect in the arms, the decreased circumference of the arms ranged from 2 to 9 cm (average 5.3 cm). The rate of preoperative versus postoperative excess circumference decreased in range from 25 to 94.7 percent (average 65.7 percent). As for the surgical effect in the legs, half the legs showed improvement. These postoperative improvements showed no correlation with the preoperative duration of edema and excess circumference in either the upper or lower extremities. Histologically, in the initial stage of lymphedema, there was destruction of both endothelial cells and smooth muscle cells in the proximal level of the lymphatic trunks. The lumen of some proximal trunks was then occluded by organization with a few small recanalizations, but the distal lymphatics remained patent with minimal destruction of both the endothelial cells and the smooth muscle cells even in the later stage of lymphedema. These results suggest that the occlusions of the lymphatic trunks and degeneration of the smooth muscle cells may start from the proximal ends of the extremities and that the timing of the occlusions and the degeneration of smooth muscle cells may not correspond to the duration of edema. It is also considered that because of the smooth muscle degeneration, the lymph-drainage capacity of the lymphatic trunks may be remarkably weakened in the proximal lymphatics of the extremities. Therefore, it is suggested that the remaining lymphatic drainage function with the smooth muscle cells may correlate with the postoperative improvement of edema. It is also suggested that the preoperative ultrastructural examination of the lymph-drainage capacity may be a suitable method for predicting the surgical effect and operative indication for lymphatic edema in the extremities.</EA>
<CC>002B12B04</CC>
<FD>Lymphoedème; Traitement; Anastomose chirurgicale; Lymphaticoveineux; Exploration; Préopératoire; Anatomopathologie; Ultrastructure; Pronostic; Etude cas; Adulte</FD>
<FG>Homme; Appareil circulatoire pathologie; Lymphatique pathologie; Chirurgie</FG>
<ED>Lymphedema; Treatment; Surgical anastomosis; Lymphaticovenous; Exploration; Preoperative; Pathology; Ultrastructure; Prognosis; Case study; Adult</ED>
<EG>Human; Cardiovascular disease; Lymphatic vessel disease; Surgery</EG>
<GD>Aufbereiten</GD>
<SD>Linfedema; Tratamiento; Anastomosis quirúrgica; Linfaticovenoso; Exploración; Preoperatorio; Anatomía patológica; Ultraestructura; Pronóstico; Estudio caso; Adulto</SD>
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<ID>96-0130969</ID>
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Ultrastructural observations of lymphatic vessels in lymphedema in human extremities. Discussion

Ultrastructural observations of lymphatic vessels in lymphedema in human extremities. Discussion

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